Long term outcomes of dilated cardiomyopathy patients

posted Jan 26, 2017, 1:34 AM by sourav ghosh
Ajay Bahl
Department of cardiology, PGIMER, Chandigarh, India

Long term outcomes of patients with dilated cardiomyopathy (DCM) have improved with medical therapy. In our cohort, with currently recommended medical therapy, one-fourth patients with non-ischemic DCM had sustained improvement, and over one-third of those who improved, relapsed. QRS duration predicted both recovery and relapse. Survival of patients in the improved group was significantly better than the non-improved groups. 
Forty DCM patients in our cohort who were very long term survivors were studied. These patients had survived for more than 10 years from initial diagnosis. A significant number of patients (45%) among this cohort had sustained recovery in ejection fraction and a large majority of our patients (90%) were either in NYHA class I or II at the end of study period. Narrow QRS at baseline, younger age at onset, smaller left atrial diameter, smaller left ventricular end diastolic diameter and lower grade of mitral regurgitation and pulmonary arterial hypertension were significant parameters in predicting good long-term outcomes.